Mutation Research-fundamental And Molecular Mechanisms Of Mutagenesis

杂志介绍

Mutation Research-fundamental And Molecular Mechanisms Of Mutagenesis杂志介绍

《Mutation Research-fundamental And Molecular Mechanisms Of Mutagenesis》是一本以English为主的未开放获取国际优秀期刊，中文名称突变研究-突变发生的基本和分子机制，本刊主要出版、报道医学-BIOTECHNOLOGY & APPLIED MICROBIOLOGY领域的研究动态以及在该领域取得的各方面的经验和科研成果，介绍该领域有关本专业的最新进展，探讨行业发展的思路和方法，以促进学术信息交流，提高行业发展。该刊已被国际权威数据库SCIE收录，为该领域相关学科的发展起到了良好的推动作用，也得到了本专业人员的广泛认可。该刊最新影响因子为1.5，最新CiteScore 指数为4.9。

本刊近期中国学者发表的论文主要有：

• High concentration of sugars is genotoxic to folate-deficient cells

  Author: Xihan Guo, Xueqin Dai, Juan Ni, Neng Cao, Guofang Yang, Jinglun Xue, Xu Wang

• Mutation analysis of ZP1, ZP2, ZP3 and ZP4 genes in 152 Han Chinese samples with ovarian endometriosis

  Author: Yang Zou, Jiang-Yan Zhou, Jiu-Bai Guo, Zi-Yu Zhang, Yong Luo, Fa-Ying Liu, Huang Huang, Feng Wang, Ming He, Li-Qun Wang, Ou-Ping Huang

• Is level of acetylation directly correlated to radiation sensitivity of cancer cell?

  Author: Fengqiu Zhang, Zhu Chen, Changsheng Shao, Qing Huang

• p.Val19Glyfs*21 and p.Leu228* variants in the survival of motor neuron 1 trigger nonsense-mediated mRNA decay causing the SMN1 PTC+ transcripts degradation

  Author: Yu-jin Qu, Lin Ge, Jin-li Bai, Yan-yan Cao, Yu-wei Jin, Hong Wang, Lan Yang, Fang Song

英文介绍

Mutation Research-fundamental And Molecular Mechanisms Of Mutagenesis杂志英文介绍

Mutation Research (MR) provides a platform for publishing all aspects of DNA mutations and epimutations, from basic evolutionary aspects to translational applications in genetic and epigenetic diagnostics and therapy. Mutations are defined as all possible alterations in DNA sequence and sequence organization, from point mutations to genome structural variation, chromosomal aberrations and aneuploidy. Epimutations are defined as alterations in the epigenome, i.e., changes in DNA methylation, histone modification and small regulatory RNAs.

MR publishes articles in the following areas:

Of special interest are basic mechanisms through which DNA damage and mutations impact development and differentiation, stem cell biology and cell fate in general, including various forms of cell death and cellular senescence.

The study of genome instability in human molecular epidemiology and in relation to complex phenotypes, such as human disease, is considered a growing area of importance.

Mechanisms of (epi)mutation induction, for example, during DNA repair, replication or recombination; novel methods of (epi)mutation detection, with a focus on ultra-high-throughput sequencing.

Landscape of somatic mutations and epimutations in cancer and aging.

Role of de novo mutations in human disease and aging; mutations in population genomics.

Interactions between mutations and epimutations.

The role of epimutations in chromatin structure and function.

Mitochondrial DNA mutations and their consequences in terms of human disease and aging.

Novel ways to generate mutations and epimutations in cell lines and animal models.