Biopharmaceutics & Drug Disposition

杂志介绍

Biopharmaceutics & Drug Disposition杂志介绍

《Biopharmaceutics & Drug Disposition》是一本以English为主的混合获取国际优秀期刊，中文名称生物制药与药物处置，本刊主要出版、报道医学-PHARMACOLOGY & PHARMACY领域的研究动态以及在该领域取得的各方面的经验和科研成果，介绍该领域有关本专业的最新进展，探讨行业发展的思路和方法，以促进学术信息交流，提高行业发展。该刊已被国际权威数据库SCIE收录，为该领域相关学科的发展起到了良好的推动作用，也得到了本专业人员的广泛认可。该刊最新影响因子为1.7，最新CiteScore 指数为3.6。

本刊近期中国学者发表的论文主要有：

• Effect of high uric acid on the disposition of metformin: in vivo and in vitro studies.

  Author: Zhang G¹, Ma Y¹, Xi D², Rao Z¹, Sun X^1,3, Wu X¹.

• TGF-β1 elevates P-gp and BCRP in hepatocellular carcinoma through HOTAIR/miR-145 axis.

  Author: Kong J¹, Qiu Y¹, Li Y¹, Zhang H¹, Wang W¹.

• Investigating the bioavailabilities of olerciamide A via the rat's hepatic, gastric and intestinal first-pass effect models.

  Author: Zhao C¹, Ying Z², Hao D¹, Zhang W¹, Ying X¹, Yang G².

• Mechanistic study of absorption and first-pass metabolism of GL-V9, a derivative of wogonin.

  Author: Xing H¹, Ren C¹, Kong Y¹, Ning C¹, Kong D¹, Zhang Y¹, Zhao D¹, Li N¹, Wang Z¹, Chen X¹, Lu Y¹.

英文介绍

Biopharmaceutics & Drug Disposition杂志英文介绍

Biopharmaceutics & Drug Dispositionpublishes original review articles, short communications, and reports in biopharmaceutics, drug disposition, pharmacokinetics and pharmacodynamics, especially those that have a direct relation to the drug discovery/development and the therapeutic use of drugs. These includes:

- animal and human pharmacological studies that focus on therapeutic response. pharmacodynamics, and toxicity related to plasma and tissue concentrations of drugs and their metabolites,

- in vitro and in vivo drug absorption, distribution, metabolism, transport, and excretion studies that facilitate investigations related to the use of drugs in man

- studies on membrane transport and enzymes, including their regulation and the impact of pharmacogenomics on drug absorption and disposition,

- simulation and modeling in drug discovery and development

- theoretical treatises

- includes themed issues and reviews

and exclude manuscripts on

- bioavailability studies reporting only on simple PK parameters such as Cmax, tmax and t1/2 without mechanistic interpretation

- analytical methods